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Icos Corporation (trademark ICOS) was an American biotechnology company and the largest biotechnology company in the U.S. state of Washington, before it was sold to Eli Lilly and Company in 2007. It was founded in 1989 by David Blech, Isaac Blech, Robert Nowinski, and George Rathmann, a pioneer in the industry and chief executive officer (CEO) and co-founder of Amgen, Icos focused on the development of drugs to treat inflammatory disorders. During its 17-year history, the company conducted clinical trials of twelve drugs, three of which reached the last phase of clinical trials. Icos also manufactured antibodies for other biotechnology companies.
Icos is famous for tadalafil (Cialis), a drug used to treat erectile dysfunction. This drug was discovered by GlaxoSmithKline, developed by Icos, and manufactured and marketed in partnership with Eli Lilly. Boosted by a unique advertising campaign led by the Grey Worldwide Agency, sales from Cialis allowed Icos to become profitable in 2006. Cialis was the only drug developed by the company to be approved. LeukArrest, a drug to treat shock, and Pafase, developed for sepsis, were both tested in phase III clinical trials, but testing was discontinued after unpromising results during the trials. Eli Lilly acquired Icos in January 2007, and most of Icos's workers were laid off soon after. CMC Biologics, a Danish contract manufacturer, bought the remnants of Icos and retained the remaining employees.

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  1. R

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    Boiler is completely dead won't do a thing but display shows -. Any ideas guys. Boilers a pile of ****e
  2. G

    Icos M3080

    Hi guys just a query concerning my Icos M3080, it's coming up 13 years old now and yes I know I'm on borrowed time and indeed the flame code comes up occasionally but a touch of the reset sorts it, it purrs away and heats the home very well, my question is recently I had a heating installer in...
  3. N

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  4. D

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  5. O

    Ideal Icos sounding like it's working all the time!

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  6. R

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  7. B

    ideal icos he18

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  8. H

    Ideal Icos HE15, hot water query

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  9. U

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  10. J

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    Hi, New to the forum, with limited plumbing / CH knowledge, so any assistance would be greatly appreciated. My set up - Ideal icos boiler, Siemens RWB29 programmer, Siemens thermostat, Megaflo CL170HE water tank. Already installed in my home (roughly 8 years old) which I purchased a year ago...
    • JackA2288
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    • Replies: 10
    • Forum: Plumbing Jobs | The Job-board
  11. M

    icos m3080 boiler fault. engineer says there is a crack in system

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  12. U

    Ideal Icos HE15 not firing up when programmer hot water on, heating OK

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  13. J

    Noisy icos

    Hi. Be most grateful for any advice from the learned. I've been to one of these that intermittently cycles with a very loud deep vibrating noise. Sounds respiration based. Does it with the front off also so not flue seals I'm thinking? Doesn't change if I touch/move fan. Flue. Condense clear...
  14. R

    Ideal Icos, no heating

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  15. I

    Ideal Icos HE12 keeps firing

    Hi, My HE12 boiler keeps firing even when the timer is off. The only way to stop it is to turn it off by the switch. I think the heating motorised valve is sticking, would this cause the boiler to keep running? Also, if I don't switch the the power off to the thermostat, pump etc, the pump...
  16. S

    Help wanted Ideal icos boiler probem

    Hi all thisis my first posting and need help. I have anIdeal Icos HE18 boiler, the other day the heating did not come on and afterinspection of the boiler. On the control panel it was flashing a code of L.F Accordingto the service manual it is a flame detection electrode fault to which...
  17. F

    Ideal Icos - Intermittent Leak

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  18. B

    Ideal icos fan resistance

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  19. J

    Icos HE15 constant issues....

    Good morning I currently have an ideal Icos HE15 and I currently don't have heating or hot water. if I had the boiler off and then turned it back on again. I get the start up, then the number 1 comes up on the panel. Then everything clicks off and I get a constant zero and no burner...
  20. D

    Icos HE15 - LF fault

    Hi all. I have the above boiler that has developed the LF fault. My gas guy has replaced 2 electrodes but still no joy. He is coming back tmw and said it could be the spark generator or the gas valve or the pcb. I have no problem in replacing the dodgy part but I don't want to keep forking out...
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