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icos
Icos Corporation (trademark ICOS) was an American biotechnology company and the largest biotechnology company in the U.S. state of Washington, before it was sold to Eli Lilly and Company in 2007. It was founded in 1989 by David Blech, Isaac Blech, Robert Nowinski, and George Rathmann, a pioneer in the industry and chief executive officer (CEO) and co-founder of Amgen, Icos focused on the development of drugs to treat inflammatory disorders. During its 17-year history, the company conducted clinical trials of twelve drugs, three of which reached the last phase of clinical trials. Icos also manufactured antibodies for other biotechnology companies.
Icos is famous for tadalafil (Cialis), a drug used to treat erectile dysfunction. This drug was discovered by GlaxoSmithKline, developed by Icos, and manufactured and marketed in partnership with Eli Lilly. Boosted by a unique advertising campaign led by the Grey Worldwide Agency, sales from Cialis allowed Icos to become profitable in 2006. Cialis was the only drug developed by the company to be approved. LeukArrest, a drug to treat shock, and Pafase, developed for sepsis, were both tested in phase III clinical trials, but testing was discontinued after unpromising results during the trials. Eli Lilly acquired Icos in January 2007, and most of Icos's workers were laid off soon after. CMC Biologics, a Danish contract manufacturer, bought the remnants of Icos and retained the remaining employees.
Got called to a house today about 3.00pm (just got home at 8.00pm) I was on another job. Customer says LF fault on boiler (Ideal Icos) so on the way home I called into merchants picked up the usual stuff for this - dare I call it a boiler.
First things first Tightness test or in this instance...
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Hi, I have an Ideal Icos bolier that exits out in to my back garden where we plan to erect a consevatory. My question is, can I simply add a 90degree conector where it exits the house and extend the flue up the wall and out the consevatory roof?
Regards
PW
Pompeywasp
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Hi, My elderly parents have just had a Ideal ICOS HE18 boiler installed, and I would like to know if its normal for the LED light to be flashing for about 5 minutes at a time before it eventually stays on continuously until switched off by the timer.
Unfortunately I wasnt around when the...
hevp123
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Anyone have thoughts or direct experience of using refurbished PCBs? Ideal icos HE12 is lights out and client on a very tight budget. Don't touch or go for it?
Hi can anyone help with two seperate boiler faults 1) baxi 105e no dhw intermitent then 1st fault light flashing ) i reset and everything fine till i was gone. checked flame sensing probe and dhw flow switch, called back and changed diaphram. all ok till later fault light flashing no hot water...
biddy.63
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Hi guys, I have been reading through the posts and know you must be annoyed with all us new guys wanting advice on how to become Gas safe engineers. Am sorry to have to ask you, but i am just after a little advice.
I have just started my NVQ 3. I am working with a Gas engineer and have been for...
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Hi all,
Did a power flush for a guy with an ideal icos boiler about 7 months ago, recently they have got back in touch as the boiler makes a "funny screachy noise" but it only happens when the boiler kicks in first thing in the morning, i went over at 4 pm and it was quiet as a mouse, what...
I have a icos ideal boiler in a new house plumbed with 10mm flexi hose, i have removed a radiator and capped the ends but now my boiler wont fire up and the pump/motor in the airing cupboard is getting really hot and making a noise, by doing this have i stopped the continual water flow or...
spander
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Hi
I dont know if anyone can help, but, Im so fed up with problems from our boiler. We have an Ideal HE24 ICOS system, its just about 4 years old. It
hasnt been a problem till the last few weeks, but it now seems to be ongoing probs. It stopped working(it went on after reset button pressed...
blondie
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Hi
Went down to my local suppliers today to price a cheap boiler for a landlords property they offered me a ideal Esprit 30 kw inc flue and clock band A forr £399 + vat as anybody fitted one of these I usully fit Baxi or when a cheap option is needed i fit maine but am considering this boiler...
andf380
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hello does anyone know any faults or the codes for this boiler hae looked on the internet but cant find them and its to late to ring ideal ! the codes were lf then changed to h flash then e and alternated between the two thanks
danielp
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I have a meeting on Thursday with a local letting agent who has 300 hundred property's on his books all needing certs. the question is what should I be charging for these some will have more than one appliance and some will need servicing I would like to get the work but don't want to be a busy...
bonesy60
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Folks,
A strange problem so any guidance would be mucho appreciated.
I have a heat only Ideal Icos 24, installed approx 36 months ago which is used to charge the Thermal store. The issue I have is that when the boiler is asked to heat the store, either through CH just starting or HW...
DOUBLEPLUG
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Hi, having an issue with my boiler. It is flashing up with the fault code 'F' then 'L'. According to the manual this is a failure to light. Just wanna say here that I'm not Gas safe registered butI am a competent plumber.
I've gone through the fault finding list in the manual and so far...
willing2learn
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please could any one advise me on how much more efficant is a sealed system to an open vented one.mine is open vented but i may make into sealed system as my boiler is a ideal icos he.
regards paul
paulgid
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just reading through existing posts this week, im seeing a vailants and ideals with problems followed closely by worchester. I know its relative to how many are installed, and obviously more of them are installed because they are well known and asked for by clients.
as installers, in your area...
migoplumber
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hi all been to look an ideal icos and the boiler is leaking and i have no idea where from its coming from the back somewhere but other than that i dont have a clue any help much appreciated. the water is slightly milky.
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