Try this method:
1. Remove all TRV heads and set any wheel valves to full open
2. Adjust all lockshield valves to 1/3 turn open
3. Get the system up to temperature (Set room stat high so the boiler does not modulate down.)
4. Measure the differential at boiler and across each rad.
5. Open the LS valves of rads with a relatively high differential by 1/12 turn or less.
6. Wait 5 - 10 minutes
7. Recheck all differentials
8. Repeat from 5 until all differentials are approximately the same.
Do not expect perfection.
It's more important to have a consistent differential than to have a specific temperature as this may not be achievable.
If the differential is less than 10C set the pump to a lower speed; if greater than 20C set to a higher speed.
Tried that, turned all rads to 1/3 open and none of the down stairs rads got warm so turned the upstairs to 1/4 and down stairs to 1/2. All rads heated up. Temp difference was around 16-18 difference. Went round all rads to get roughly that now upstairs are heating up but down stairs taking a lot longer.
Close to giving up is it so much to ask to have a heating system that works lol