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Glycosyltransferase-like protein LARGE1 is an enzyme that in humans is encoded by the LARGE gene.

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  1. J

    Oil boiler size for large house

    Hi I’m looking to buy a new Combi oil boiler but don’t know what size to go for my old boiler was a Worcester heatslave 12/14 which was running originally 12 rads and one bathroom when I moved in. I then added a rad I believe it was to small to begin with as it was always breaking down it now...
  2. M

    Large 15mm brass olives

    Anywhere no where they may sell 15mm brass olives that are really meaty kind of like dome shaped? I want them for doing refurb work when taking old showers off to aquapanel the walls. The olives that were on originally are a lot bigger than the ones mainly available now. Thanks.
  3. S

    Historical Question: very large loft storage tanks (old houses)

    My house was built in 1902 and still has a gravity fed system with a cold storage tank in the loft. Nowadays we have quite a small plastic storage tank (50 Imperial gallons) but the old tank was much, much bigger than this. The original tank started to leak when I was a child about 40 years ago...
  4. I

    Large bore waste pipe cracked

    hi guys, got called out to local cafe regarding leaking waste pipe. took 32mm pipe, 40mm pipe, solvent weld, compression fittings, elbows, tees and couplings, got to job and bugger me if it ain’t 60mm pipe that has cracked on a tee in the most awkward place. Everything is fitted with solvent...
  5. J

    UFCH and a large Stove

    Hi All, I'm renovating an old cottage and will be installing UFCH with an Air to water heat pump. I'm building an extension off the cottage which will include a kitchen/utility and bathroom so it will basically be 3 Zones, Kitchen, Livingroom and 1 bedroom. The living room is 7 m x 4.5 m with a...
  6. G

    Large Extension - Oil Boiler Advice + UFH

    we are planing a large 11m x 11m 1.5 storey extension on the side of our house. We have no access to mains gas. Our current setup is as follows: (installed in a new build 5 years ago) 4 Beds 3 Baths worcester bosch combi boiler (located in car port/shed detached from house) UFH downstairs - 5...
  7. townfanjon

    I need some therapy guys, or a large glass of JD .

    Rant ... approx 15 years ago 2 council guys rocked up out of the blue and told us we have a public footpath running through our garden , oh great , cost then around 2K to shift it , after several letters etc they said that because they knew we didnt built the house and garden over the footpath...
  8. D

    External kitchen drainage - (large) leak

    Hi - first time poster so apologies if this isn't in the correct forum. A couple of days ago I noticed that my kitchen drainage pipe is overflowing if the water is run for more than 10-20 seconds. I'd assumed the chamber it flows into (grease trap?) was blocked and just needed clearing, but on...
  9. Michael Groves

    15M pump required, one large Vs 2 small in series?

    I'm specifying a new system. It has a 15M head, I called Grundfos and they recommended Magna3 40-150 rrp £1,640. (using rrp for reference only) A friend recommended 2 no. Grundfos Magna3 32-80 in series, rrp £628 (Total £1,256). Running costs of 2no. 32-80 is a third of 40-150. Grundfos...
  10. R

    Combi boiler in a large house

    Good afternoon, We are looking to change our existing system (boiler, cylinder and massive water tank in the loft) and have been advised on a Megaflow and a Combi boiler from different plumbers. I am really keen on a combi boiler (water on demand, no tanks etc), though understood they were...
  11. cr0ft

    Temperature problems with large commercial hot water system

    Hi all. As most of you will know I've gone back on the cards now and am now fault-finding one of our commercial hot water systems in a 5,800sq.m building. It's a large building on a hospital site. The hot water system is an old system! Heating is run from a steam feed from the main hospital...
  12. G

    Smart Thermostat Megaflow & Underfloor Heating For Large Extension

    Hi All, After spending countless hours researching and driving myself mad i was hoping someone with experience might be able to offer some advice. We are totally renovating our house and installing a new boiler with megaflo style water system, and wet underfloor heating in a new large open...
  13. D

    Advice required: Heating a large volume of water with LPG Gas boiler

    First time posting on here and I am after some help and advice on a project I have ongoing at home - a bit cheeky I know but as they say around here ‘Shy bairnes get nowt’! My children (10 and 8 at the time) were lucky enough to be given an above ground 15ft round swimming pool from some...
  14. cr0ft

    Capping off large gas meters

    Folks, Went to a job today to cap off a very large gas meter. Didn't quote for it as the pipe coming out was 2.5" LCS and I wouldn't have a clue where to get caps for the meter. They just want the gas supply disconnecting and the meter capped off. Can you do this on a domestic ticket or does...
  15. S

    Oil to storage heaters in large house.

    My aunt has bought a large 3 bedroom house and has removed the oil tank and is also wanting to remove the oil burner and change from oil to electric storage heaters. I've been trying to advise her against this because the running costs of storage heaters can be more than oil. Does building regs...
  16. T

    System boiler/hot water cylinder spec for large property

    Hi there, My hubby and I are in the middle of a renovation that's turned out to be the equivalent of a new build. We've had to change everything apart from the envelope including all the plumbing and electrics. The property is approx 260sq m on 3 floors and has a total of 9 rooms, 2 kitchens...
  17. M

    Fixing large radiator to soft breeze wall

    How have people hung large rads before on the really soft spongy breeze they use to use on houses?
  18. B

    starting an emergency lear repair service

    Hi all, I have just registered with this site...I am mainly a kitchen/bathroom installer but carry out most home renovations and have been doing so for the last 20 odd years. I am located in north London and am thinking of focussing on a call out emergency service aimed at north London. I...
  19. P

    Black Friday powertool deals

    There's some good stuff on FFX like this jacket.. Milwaukee 4939434899XL 2016 BMW Team Fleece Extra Large Same im not XL but its worth bulking out just so I can get it for £20! Roll on the Axminster one, anyone seen ant good deals?
  20. D

    Large vertical radiator hanging

    Hi I have to fit a 1800x400 double radiator and have a query as to how to fit the bottom cup brackets, I have attaced link and the diagram (c) shows the bottom brackets pointing down, is this correct for such a large radiator, I am unable to find any further information on the net and wondered...
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