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bodies
Inclusion bodies are aggregates of specific types of protein found in neurons, a number of tissue cells including red blood cells, bacteria, viruses, and plants. Inclusion bodies of aggregations of multiple proteins are also found in muscle cells affected by inclusion body myositis and hereditary inclusion body myopathy.Inclusion bodies in neurons may be accumulated in the cytoplasm or nucleus, and are associated with many neurodegenerative diseases.
Inclusion bodies in neurodegenerative diseases are aggregates of misfolded proteins (aggresomes) and are hallmarks of many of these diseases, including Lewy bodies in Lewy body dementias, and Parkinson's disease, neuroserpin inclusion bodies called Collins bodies in familial encephalopathy with neuroserpin inclusion bodies, inclusion bodies in Huntington's disease, Papp-Lantos inclusions in multiple system atrophy, and various inclusion bodies in frontotemporal dementia including Pick bodies. Bunina bodies in motor neurons are a core feature of amyotrophic lateral sclerosis.Other usual cell inclusions are often temporary inclusions of accumulated proteins, fats, secretory granules or other insoluble components.Inclusion bodies are found in bacteria as particles of aggregated protein. They have a higher density than many other cell components but are porous. They typically represent sites of viral multiplication in a bacterium or a eukaryotic cell and usually consist of viral capsid proteins.
Inclusion bodies contain very little host protein, ribosomal components or DNA/RNA fragments. They often almost exclusively contain the over-expressed protein and aggregation and has been reported to be reversible. It has been suggested that inclusion bodies are dynamic structures formed by an unbalanced equilibrium between aggregated and soluble proteins of Escherichia coli. There is a growing body of information indicating that formation of inclusion bodies occurs as a result of intracellular accumulation of partially folded expressed proteins which aggregate through non-covalent hydrophobic or ionic interactions or a combination of both.
What is the average hourly rate now for plumbers? Am i being Ripped off on £12 an hour?? time and a half on all call outs too, i thought it was good until i got chatting to some plumbers for other firms in the local plumb centre!
plumberdan23
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Morning All
During this lull I am looking at doing some solar/renewable training, as I have had quite a few enquiries about PV, solar hot water and air source pumps.
I have the domestic installers part p, not sure if I need full scope for the PV though.Also have the Unvented for the solar...
grahamgas
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bosch
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worcester
Finally I have my first and hopefully only MCS accreditation inspection for Heatpumps today.
This inspection is through NICEIC, so should prove to be an interesting day.
It appears the main worry is all the paperwork involved as they want a huge paper trail generated for each job, not so eco...
I don't know if this question has been asked previously, I don't have the time to trawl through all the posted threads.
Have any of you noticed a massive reduction in the amount of gas work you have received in the last year.
We would normally look at around 10 gas related jobs a day in the...
pureplumber
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bodies
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Colleges are taking flak but it appears its not their fault!
Vocational students left in the dark as qualifications undergo reform | Education | The Guardian
try this
fuzzy
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Just fitted new taps in basin and bath ,if you turn basin hot tap on slightly it dribbles, vibrates and makes a painfull noise but turn it on a bit more and it shoots water out and both noise and vibration disapear.also when you turn on basin cold tap slighly you get a dribble but once you turn...
PETEWEST
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Hi all. Have just joined the forum. Have years of DIY plumbing experience though not with any new whizzy systems, mostly trad gravity/copper/solder etc but whole systems . I've just been issued compliancy instructions by local water authority to create an AA airgap on existing std 50gal gravity...
PJMallinson
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I am coming to the end of my 6128 course and was wondering what clubs I need to join to be able to actually work as it seems I can't fart without having to get someone out to certify it. Here is a list of qualifications I will hopefully get:
· City & Guilds 6128 Technical Certificate...
kmcolshaw
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unvented
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hope theses 2 pics give some idea as to what happend to me today, half an hour after after working in this plantroom - didnt feel to clever, got headache just felt dodgy, went to van got analyser and hey presto 50ppm carbon monoxide - not bad for a boiler serviced 3 months ago by our companies...
migoplumber
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just wonderd what your thourghts weren on this subject?
Do you think Plumbing should go the same way as gas, i.e ran by a body
must get the quals, id card ect.
give it some pros & cons.
bodies
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Hi all of you.
Just starting out, and wondered which if any are the best/most advised and respected trade association/s to join.
I have read a couple of posts about CIPHE and FSB etc, but there appear to be so many.
Obviously Gas Safe is a must if venturing into that field but what others are...
JSPM
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bodies
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gas safe
industry
safe
starting out
trade
train
which
Had a quick question about TRV vs manual valves for radiators.
I have a small house (2 bedrooms upstairs / box room / bathroom and downstiars kitchen / cloakroom / lounge) and have bought Ancona 3 col radiators to try and match the period of the house (1890's granite cottage).
For...
edwardk
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bathroom
bodies
brass
building
building regs
cheap
efficiency
gas
granite
head
heating
hot
kitchen
manual
radiator
radiator valves
radiators
replacement
sale
trade
trv
valve
valves
A life time of plumbing has taken its toll, the bodies weak and some say the mind. I applied for a window cleaning job in Amsterdam but was rejected. Looking at other options to relieve boredom and fund retirement i have built a couple of studio apartments for holiday rental. Wadebridge...
Does any of you chaps know if there is a compatible pump head for this boiler other than the OEM type (bosch branded) which is not stocked by my local supplier. I could order for friday but 3 kids no boiler I would like to sort it first thing tomorrow , cheers
as i live in wales, once i finish my level 3 i would like to look into oil and lpg, as far as i can gather i have to complete the 101+105e in oil and for the lpg the changeover course conolp1pd? also the res homes and leisure veh would help with me being near coast resorts.
my question is this...
moony
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hi i am working with to gas safe engineers at the moment and im interested in getting my gas cert i havent got the money to do the course yet so im just see ing if i can get my portfolio to do but i dont no how to get hold of one can some pleassssseee help me many thanks
karloss123
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bodies
bpec
buy
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Looking at previous posts, it is quite clear that people working in the trade are at odds as to what you can and can't do regarding the boiler area if you're not qualified, also with the water side of the boiler(me included).
Would it maybe be possible to get someone from one of the professional...
bodies
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central heating system
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Hi, quick question. Are non-gas safe registered plumbers allowed to fix leaks on boilers eg heat exchanger as long as the gas train isn't broken?
Thanks in advance :)
willing2learn
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train
work
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