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Is it possible, say, when you have a leak around a basin, bath or shower from a hole in the silicone. Can you apply a bit on top to cure leak? Or, do you need to renew the whole seal?
You can if it's only a small leak. If the leak is at the edges where the seal is made, it's best to rake it all out with a knife and silicon remover and redo it. If silicon is leaking at any point, my preference is to renew the lot.
On the subject of silicon, a polysulphide based mastic is far better as it seals better, remains more flexible and sticks to anything if the correct brush on primer is used. It can also be used outdoors and the sheet lead sealant you see on sale is this stuff.
Somtimes it can be a pain in the botty to get silicon to adhere to aluminium on some shower frames. Tool station sell the poly stuff.